Thursday, February 27, 2014

Basic Concepts in Medicinal Chemistry


Basic Concepts in Medicinal Chemistry [Paperback]

Author: Amazon Prime | Language: English | ISBN: 1585282669 | Format: PDF, EPUB

Basic Concepts in Medicinal Chemistry
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Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation.

In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group. Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups. How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism. Numerous examples and expanded discussions for complex concepts.Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice. An overview of structure activity relationships (SARs) and concepts that govern drug design. Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix. Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry.
Books with free ebook downloads available Basic Concepts in Medicinal Chemistry
  • Paperback: 460 pages
  • Publisher: American Society of Health-System Pharmacists; 1 edition (January 31, 2013)
  • Language: English
  • ISBN-10: 1585282669
  • ISBN-13: 978-1585282661
  • Product Dimensions: 7 x 9.8 inches
  • Shipping Weight: 1.8 pounds (View shipping rates and policies)
  • Amazon Best Sellers Rank: #189,424 in Books (See Top 100 in Books)
This book makes Medicinal Chemistry make sense. It's laid out in easy to digest chapters with lots of examples and practice problems. Other books I've read on the subject aren't written for someone with not a lot of background in Chemistry, so they were difficult and muddy. Harrold and Zavod did a great job providing a breakdown of the fundamental pieces of Medicinal Chemistry. I honestly enjoyed reading this book and understand so much more of the foundational pieces I need for my continuing years in Pharmacy School. I would highly recommend everyone that's looking for a place to start or to solidify their skills to read this book. It's the one book I will definitely use over again.
By SydneyDAK
Great review text, but wouldn't recommend for sole source of information. However the practice problems are top notch. For more in-depth medicinal/pharmaceutical chemistry try Silverman instead.
By Nick

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